Haseman Elston Regression in Ascertained Samples: Importance of Dependent Variable and Mean Correction Factor Selection
نویسندگان
چکیده
منابع مشابه
Haseman-Elston regression in ascertained samples: importance of dependent variable and mean correction factor selection.
OBJECTIVE One of the first tools for performing linkage analysis, Haseman-Elston regression (HE), has been successfully used to identify linkages to several disease traits. A recent explosion in extensions of HE leaves one faced with the task of choosing a flavor of HE best suited for a given situation. This paper puts this dilemma into perspective and proposes a modification to HE for highly a...
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ژورنال
عنوان ژورنال: Human Heredity
سال: 2007
ISSN: 0001-5652,1423-0062
DOI: 10.1159/000108938